Diabetes genes
A study published today in Nature Genetics has identified nine new candidate genes associated with diabetes. These genes play a role in the expression and movement of GLUT4, a key glucose transporter in muscle and fat cells that is responsible for glucose uptake after a meal. by author with ChatGPT and Bing Image Creator The research suggests that these genes affect the amount of GLUT4 found on the cell surface, which influences the cell's ability to remove glucose from the blood. Genetic susceptibility to diabetes has been a subject of intensive study for nearly five decades. Type 1 diabetes (T1D) is believed to be triggered by an initial event followed by autoimmune destruction of pancreatic cells. The risk for monozygotic twins of patients with type 1A diabetes has been known to not be 100% . The strongest genetic predictor of T1D risk is the Human Leukocyte Antigen (HLA) association, particularly the genes in the HLA class I and class II regions (known ...